The Inactivation Effect of Potassium Monopersulfate Compound (PMPS) on African Swine Fever Virus (ASFV)

1. Introduction of potassium monopersulfate compound (PMPS)

Potassium monopersulfate compound (for short, PMPS or KMPS) is a kind of free-flowing white granular or powder, which includes three types of component: potassium monopersulfate (KHSO₅), potassium hydrogen sulfate (KHSO₄) and potassium sulfate (K₂SO₄). Thereinto, KHSO₅ is the active component whose proportion is over 42.8 ~ 46w/% in usual. The active oxygen content is 4.5 ~ 4.9 w/%.

The action mechanism of PMPS is: through a chain reaction in water, hypochloric acid, active oxygen, free hydroxyl group and hydrogen peroxide are produced continuously. They can interfere with the DNA and RNA synthesis of pathogens, coagulate and denature the proteins of pathogens, further interfere with the activity of the enzyme system of pathogens, affect its metabolism, increase the permeability of cell membrane, cause the loss of enzymes and nutrients, dissolve and breaks the pathogens, and then kill the pathogens. PMPS also has strong acidity (pH value of 2.2 ~ 2.6), can kill a variety of pathogenic micro-organisms, and is not affected by organic matter, its metabolites will not affect people, animals and the environment.

2. Introduction of African Swine Fever Virus (ASFV)

African swine fever (ASF) is a virulent infectious disease caused by African swine fever virus (ASFV) in domestic pigs and wild boars. Pigs of different ages are susceptible, and the morbidity and mortality can be as high as 100%.

In China, the African swine fever epidemic in 2019 caused the domestic pig stock to decrease by more than 40% compared with the same period of previous years, and the stock of breeding sows to decrease by 37.8%, resulting in continued rise in pork prices.

ASFV can survive for a long time in feces, blood, soil and wood surfaces. The prevention and control of the epidemic of ASFV mainly relies on strict biosecurity measures and effective disinfection measures. However, regular disinfection protocols for sites where other swine diseases occur might have no effect on ASFV.

3. PMPS and ASFV

In winter and spring, the temperature drops, the temperature difference between day and night is large, and the air is dry, ASFV is more likely to survive in the environment, and the health of pigs is easily affected, therefore African swine fever has entered a period of high incidence.

At present, there are many kinds of effective disinfectants for killing ASFV, among which oxidizing disinfectants have more advantages in ASFV disinfection. PMPS powder, as a kind of peroxide, can be used in the disinfection of incoming and outgoing personnel and the disinfection of pigs.

After testing the inactivated effect of ASFV by Ten commercial disinfectants, Cheng Jing and his team also confirmed the effect of PMPS on the prevention and control of ASFV infection.

Moreover, notice of the Ministry of China Agriculture and Rural Affairs on the issuance of the African Swine Fever Epidemic Emergency Implementation Plan (Second edition 2020) gave a list of recommended types and application range of disinfection products. In it, disinfectants containing PMPS are recommended for environmental and air disinfection, drinking water disinfection, clothing, hats, shoes and other items that may be contaminated disinfection, and some office living areas and personnel clothing disinfection.

Note: The above information is for reference only, if you have any questions, please contact our sales staff.

Information source

1. Zhang Jiaoer, Luo Yuzi, Sun Yue, Sun Feng, Sun Yuan, Wang Tao, Yang Yaozhi, Hao Kai, Qiu Huaji (2020), Inactivation effect of potassium peroxymonosulfate compound powder on African swine fever virus, Chinese Journal of Disinfection 2020:37(5)，321-323.
2. Li Peihong, Liu Cuixia, Wu xuefei, Tian Hongli, Zhao bianbian (2024), Study on Chemical Properties and Disinfection of Potassium Peroxymonosulfate Compound Salt, Yunnan Chemical Technology Jan 2024 Vol 51, No.1, 6-9.
3. http://www.moa.gov.cn/nybgb/2020/202006/202007/t20200714_6348531.htm
4. Cheng Jing, Xu Jian, Liu Wenxiao, Jiang Bo, Li Yongqing (2022),Inactivated Effect of African Swine Fever Virus by Ten Commercial Disinfectants, Chinese Journal of Veterinary Medicine 2022:58(3), 47-56.